DeTiN : Overcoming Tumor in Normal Contamination

A key step in achieving accurate detection of somatic mutations is comparison of sequencing data from a tumor sample to its matched germline control. Sensitivity to detect somatic variants is greatly reduced when the matched normal sample is contaminated with tumor cells. To overcome this limitation...

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Detalles Bibliográficos
Autores principales: Taylor-Weiner, Amaro, Stewart, Chip, Giordano, Thomas, Miller, Mendy, Rosenberg, Mara, Macbeth, Alyssa, Lennon, Niall, Rheinbay, Esther, Landau, Dan-Avi, Wu, Catherine J., Getz, Gad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6528031/
https://www.ncbi.nlm.nih.gov/pubmed/29941871
http://dx.doi.org/10.1038/s41592-018-0036-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6528031/
https://www.ncbi.nlm.nih.gov/pubmed/29941871
http://dx.doi.org/10.1038/s41592-018-0036-9

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