Acquired Long QT Syndrome and Electrophysiology of Torsade de Pointes

Congenital long QT syndrome (LQTS) has been the most investigated cardiac ion channelopathy. Although congenital LQTS remains the domain of cardiologists, cardiac electrophysiologists and specialised centres, the much more frequently acquired LQTS is the domain of physicians and other members of hea...

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Detalles Bibliográficos
Autores principales: El-Sherif, Nabil, Turitto, Gioia, Boutjdir, Mohamed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Radcliffe Cardiology 2019
Materias:
Electrophysiology & Ablation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6528034/
https://www.ncbi.nlm.nih.gov/pubmed/31114687
http://dx.doi.org/10.15420/aer.2019.8.3
Descripción
Sumario:Congenital long QT syndrome (LQTS) has been the most investigated cardiac ion channelopathy. Although congenital LQTS remains the domain of cardiologists, cardiac electrophysiologists and specialised centres, the much more frequently acquired LQTS is the domain of physicians and other members of healthcare teams required to make therapeutic decisions. This paper reviews the electrophysiological mechanisms of acquired LQTS, its ECG characteristics, clinical presentation, and management. The paper concludes with a comprehensive review of the electrophysiological mechanisms of torsade de pointes.

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