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Pre-clinical evaluation of Minnelide as a therapy for acute myeloid leukemia
BACKGROUND: There is an urgent need for novel and effective treatment options for acute myeloid leukemia (AML). Triptolide, a diterpenoid tri-epoxide compound isolated from the herb Tripterygium wilfordii and its water-soluble pro-drug-Minnelide have shown promising anti-cancer activity. A recent cl...
Autores principales: | Giri, Bhuwan, Gupta, Vineet K., Yaffe, Brianna, Modi, Shrey, Roy, Pooja, Sethi, Vrishketan, Lavania, Shweta P., Vickers, Selwyn M., Dudeja, Vikas, Banerjee, Sulagna, Watts, Justin, Saluja, Ashok |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6528210/ https://www.ncbi.nlm.nih.gov/pubmed/31109340 http://dx.doi.org/10.1186/s12967-019-1901-8 |
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