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Impact of cancer mutational signatures on transcription factor motifs in the human genome

BACKGROUND: Somatic mutations in cancer genomes occur through a variety of molecular mechanisms, which contribute to different mutational patterns. To summarize these, mutational signatures have been defined using a large number of cancer genomes, and related to distinct mutagenic processes. Each ca...

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Detalles Bibliográficos
Autores principales:	Yiu Chan, Calvin Wing, Gu, Zuguang, Bieg, Matthias, Eils, Roland, Herrmann, Carl
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6528224/ https://www.ncbi.nlm.nih.gov/pubmed/31109337 http://dx.doi.org/10.1186/s12920-019-0525-4

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