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APOE genotype and sex affect microglial interactions with plaques in Alzheimer’s disease mice
Microglia affect Alzheimer’s disease (AD) pathogenesis in opposing manners, by protecting against amyloid accumulation in early phases of the disease and promoting neuropathology in advanced stages. Recent research has identified specific microglial interactions with amyloid plaques that exert impor...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6528326/ https://www.ncbi.nlm.nih.gov/pubmed/31113487 http://dx.doi.org/10.1186/s40478-019-0729-z |