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APOE genotype and sex affect microglial interactions with plaques in Alzheimer’s disease mice

Microglia affect Alzheimer’s disease (AD) pathogenesis in opposing manners, by protecting against amyloid accumulation in early phases of the disease and promoting neuropathology in advanced stages. Recent research has identified specific microglial interactions with amyloid plaques that exert impor...

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Detalles Bibliográficos
Autores principales:	Stephen, T. L., Cacciottolo, M., Balu, D., Morgan, T. E., LaDu, M. J., Finch, C. E., Pike, C. J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6528326/ https://www.ncbi.nlm.nih.gov/pubmed/31113487 http://dx.doi.org/10.1186/s40478-019-0729-z

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