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Comparison of four DLL3 antibodies performance in high grade neuroendocrine lung tumor samples and cell cultures

BACKGROUND: Small cell lung cancer (SCLC) is usually diagnosed in the advanced stage. It has a very poor prognosis, with no advancements in therapy in the last few decades. A recent phase 1 clinical study, using an antibody-drug conjugate directed against DLL3, showed promising results. A prerequisi...

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Detalles Bibliográficos
Autores principales:	Brcic, Luka, Kuchler, Christian, Eidenhammer, Sylvia, Pabst, Daniela, Quehenberger, Franz, Gazdar, Adi F., Popper, Helmut
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6528329/ https://www.ncbi.nlm.nih.gov/pubmed/31109352 http://dx.doi.org/10.1186/s13000-019-0827-z

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