Altered detrusor contractility and voiding patterns in mice lacking the mechanosensitive TREK-1 channel

BACKGROUND: Previously published results from our laboratory identified a mechano-gated two-pore domain potassium channel, TREK-1, as a main mechanosensor in the smooth muscle of the human urinary bladder. One of the limitations of in vitro experiments on isolated human detrusor included inability t...

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Detalles Bibliográficos
Autores principales: Pineda, Ricardo H., Hypolite, Joseph, Lee, Sanghee, Carrasco, Alonso, Iguchi, Nao, Meacham, Randall B., Malykhina, Anna P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6528348/
https://www.ncbi.nlm.nih.gov/pubmed/31113422
http://dx.doi.org/10.1186/s12894-019-0475-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6528348/
https://www.ncbi.nlm.nih.gov/pubmed/31113422
http://dx.doi.org/10.1186/s12894-019-0475-3

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