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Altered detrusor contractility and voiding patterns in mice lacking the mechanosensitive TREK-1 channel
BACKGROUND: Previously published results from our laboratory identified a mechano-gated two-pore domain potassium channel, TREK-1, as a main mechanosensor in the smooth muscle of the human urinary bladder. One of the limitations of in vitro experiments on isolated human detrusor included inability t...
Autores principales: | Pineda, Ricardo H., Hypolite, Joseph, Lee, Sanghee, Carrasco, Alonso, Iguchi, Nao, Meacham, Randall B., Malykhina, Anna P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6528348/ https://www.ncbi.nlm.nih.gov/pubmed/31113422 http://dx.doi.org/10.1186/s12894-019-0475-3 |
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