Cargando…
Evaluation of pathogen P21 protein as a potential modulator of the protective immunity induced by Trypanosoma cruzi attenuated parasites
BACKGROUND: TcP21 is a ubiquitous secreted protein of Trypanosoma cruzi and its recombinant form (rP21) promotes parasite cell invasion and acts as a phagocytosis inducer by activating actin polymerisation in the host cell. OBJECTIVE: Our goal was to evaluate if the additional supplementation of rP2...
Autores principales: | Pérez Brandán, Cecilia, Mesias, Andrea C, Acuña, Leonardo, Teixeira, Thaise Lara, da Silva, Claudio Vieira |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Instituto Oswaldo Cruz, Ministério da Saúde
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6528380/ https://www.ncbi.nlm.nih.gov/pubmed/31116244 http://dx.doi.org/10.1590/0074-02760180571 |
Ejemplares similares
-
Effects of IFN-γ coding plasmid supplementation in the immune response and protection elicited by Trypanosoma cruzi attenuated parasites
por: Pérez Brandán, Cecilia, et al.
Publicado: (2017) -
Knockout of the dhfr-ts Gene in Trypanosoma cruzi Generates Attenuated Parasites Able to Confer Protection against a Virulent Challenge
por: Perez Brandan, Cecilia, et al.
Publicado: (2011) -
Revealing Annexin A2 and ARF-6 enrollment during Trypanosoma cruzi extracellular amastigote-host cell interaction
por: Teixeira, Thaise Lara, et al.
Publicado: (2015) -
Ablation of the P21 Gene of Trypanosoma cruzi Provides Evidence of P21 as a Mediator in the Control of Epimastigote and Intracellular Amastigote Replication
por: Teixeira, Thaise Lara, et al.
Publicado: (2022) -
Evaluation of high efficiency gene knockout strategies for Trypanosoma cruzi
por: Xu, Dan, et al.
Publicado: (2009)