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A Single Dose of Baicalin Has No Clinically Significant Effect on the Pharmacokinetics of Cyclosporine A in Healthy Chinese Volunteers

Despite its narrow therapeutic window and large interindividual variability, cyclosporine A (CsA) is the first-line therapy following organ transplantation. Metabolized mainly by CYP3A and being a substrate of P-glycoprotein (P-gp), CsA is susceptible to drug–drug interactions. Baicalin (BG) is a dr...

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Detalles Bibliográficos
Autores principales:	Liu, Ruijuan, Li, Xia, Wei, Jingyao, Liu, Shuaibing, Chang, Yuanyuan, Zhang, Jiali, Zhang, Ji, Zhang, Xiaojian, Fuhr, Uwe, Taubert, Max, Tian, Xin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6528491/ https://www.ncbi.nlm.nih.gov/pubmed/31156436 http://dx.doi.org/10.3389/fphar.2019.00518

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