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Treatment with metformin prevents myocardial ischemia–reperfusion injury via STEAP4 signaling pathway

OBJECTIVE: The aim of the present study was to investigate the underlying mechanism of metformin in reducing myocardial apoptosis and improving mitochondrial function in rats and H9c2 cells subjected to myocardial ischemia–reperfusion (I/R) or hypoxia–reoxygenation (H/R) injuries, respectively. METH...

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Detalles Bibliográficos
Autores principales: Luo, Ting, Zeng, Xianli, Yang, Wenqi, Zhang, Yuelan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Kare Publishing 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6528516/
https://www.ncbi.nlm.nih.gov/pubmed/31062756
http://dx.doi.org/10.14744/AnatolJCardiol.2019.11456