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Efficiently activated ε‐poly‐L‐lysine production by multiple antibiotic‐resistance mutations and acidic pH shock optimization in Streptomyces albulus

ε‐Poly‐L‐lysine (ε‐PL) is a food additive produced by Streptomyces and is widely used in many countries. Working with Streptomyces albulus FEEL‐1, we established a method to activate ε‐PL synthesis by successive introduction of multiple antibiotic‐resistance mutations. Sextuple mutant R6 was finally...

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Detalles Bibliográficos
Autores principales:	Wang, Liang, Li, Shu, Zhao, Junjie, Liu, Yongjuan, Chen, Xusheng, Tang, Lei, Mao, Zhonggui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2018
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6528598/ https://www.ncbi.nlm.nih.gov/pubmed/30298553 http://dx.doi.org/10.1002/mbo3.728

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