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Aortic Strain Correlates With Elastin Fragmentation in Fibrillin-1 Hypomorphic Mice

Background: High-frequency ultrasound has facilitated in vivo measurement of murine ascending aorta, allowing aortic strain to be determined from 2-D imaging. Thoracic aortic aneurysms associated with mutations in fibrillin-1 (FBN1) display elastin fragmentation, which may affect aortic strain. In t...

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Detalles Bibliográficos
Autores principales:	Chen, Jeff Z., Sawada, Hisashi, Moorleghen, Jessica J., Weiland, Mackenzie, Daugherty, Alan, Sheppard, Mary B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Japanese Circulation Society 2019
Materias:	Original article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6528667/ https://www.ncbi.nlm.nih.gov/pubmed/31123721 http://dx.doi.org/10.1253/circrep.CR-18-0012

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