Anticonvulsant and ameliorative effects of pioglitazone on cognitive deficits, inflammation and apoptosis in the hippocampus of rat pups exposed to febrile seizure

OBJECTIVE(S): Pioglitazone (PGZ), a peroxisome proliferator-activated receptor gamma (PPAR-γ) agonist, has significant neuroprotective effects and has been reported to regulate inflammatory processes. MATERIALS AND METHODS: We evaluated the effects of PGZ on febrile seizure (FS) in rat pups. Three g...

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Detalles Bibliográficos
Autores principales: Hussein, Hussein Allawi, Moghimi, Ali, Roohbakhsh, Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6528711/
https://www.ncbi.nlm.nih.gov/pubmed/31156787
http://dx.doi.org/10.22038/ijbms.2019.35056.8339

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