Parkin-mediated ubiquitination contributes to the constitutive turnover of mitochondrial fission factor (Mff)

The mitochondrial outer membrane protein Mitochondrial Fission Factor (Mff) plays a key role in both physiological and pathological fission. It is well established that at stressed or functionally impaired mitochondria, PINK1 recruits the ubiquitin ligase Parkin which ubiquitinates Mff and other mit...

Descripción completa

Detalles Bibliográficos
Autores principales: Lee, Laura, Seager, Richard, Nakamura, Yasuko, Wilkinson, Kevin A., Henley, Jeremy M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6528996/
https://www.ncbi.nlm.nih.gov/pubmed/31112535
http://dx.doi.org/10.1371/journal.pone.0213116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6528996/
https://www.ncbi.nlm.nih.gov/pubmed/31112535
http://dx.doi.org/10.1371/journal.pone.0213116

Ejemplares similares