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Parkin-mediated ubiquitination contributes to the constitutive turnover of mitochondrial fission factor (Mff)
The mitochondrial outer membrane protein Mitochondrial Fission Factor (Mff) plays a key role in both physiological and pathological fission. It is well established that at stressed or functionally impaired mitochondria, PINK1 recruits the ubiquitin ligase Parkin which ubiquitinates Mff and other mit...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6528996/ https://www.ncbi.nlm.nih.gov/pubmed/31112535 http://dx.doi.org/10.1371/journal.pone.0213116 |