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LINC00152: A pivotal oncogenic long non‐coding RNA in human cancers
In recent years, increasing evidence has shown the potential role of long non‐coding RNAs (lncRNAs) in multiple cancers. Deregulation of lncRNAs was detected being closely associated with many kinds of tumours where they can act as a tumour suppressor or accelerator. LINC00152 was identified as an o...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6529135/ https://www.ncbi.nlm.nih.gov/pubmed/28464433 http://dx.doi.org/10.1111/cpr.12349 |
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author | Yu, Yang Yang, Jian Li, Quanpeng Xu, Boming Lian, Yifan Miao, Lin |
author_facet | Yu, Yang Yang, Jian Li, Quanpeng Xu, Boming Lian, Yifan Miao, Lin |
author_sort | Yu, Yang |
collection | PubMed |
description | In recent years, increasing evidence has shown the potential role of long non‐coding RNAs (lncRNAs) in multiple cancers. Deregulation of lncRNAs was detected being closely associated with many kinds of tumours where they can act as a tumour suppressor or accelerator. LINC00152 was identified as an oncogene involved in many kinds of cancers, such as gastric cancer, hepatocellular carcinoma, colon cancer, gallbladder cancer and renal cell carcinoma. Moreover, inhibition of LINC00152 can suppress proliferation, migration and invasion of the cancer cells. Increasing evidence has showed that LINC00152 may act as a diagnostic and prognostic biomarker for the above‐mentioned cancers. In our review, we summarize the recent research progress of the expression and role of LINC00152 in various kinds of cancers. |
format | Online Article Text |
id | pubmed-6529135 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-65291352020-03-13 LINC00152: A pivotal oncogenic long non‐coding RNA in human cancers Yu, Yang Yang, Jian Li, Quanpeng Xu, Boming Lian, Yifan Miao, Lin Cell Prolif Review Article In recent years, increasing evidence has shown the potential role of long non‐coding RNAs (lncRNAs) in multiple cancers. Deregulation of lncRNAs was detected being closely associated with many kinds of tumours where they can act as a tumour suppressor or accelerator. LINC00152 was identified as an oncogene involved in many kinds of cancers, such as gastric cancer, hepatocellular carcinoma, colon cancer, gallbladder cancer and renal cell carcinoma. Moreover, inhibition of LINC00152 can suppress proliferation, migration and invasion of the cancer cells. Increasing evidence has showed that LINC00152 may act as a diagnostic and prognostic biomarker for the above‐mentioned cancers. In our review, we summarize the recent research progress of the expression and role of LINC00152 in various kinds of cancers. John Wiley and Sons Inc. 2017-05-02 /pmc/articles/PMC6529135/ /pubmed/28464433 http://dx.doi.org/10.1111/cpr.12349 Text en © 2017 The Authors. Cell Proliferation Published by John Wiley & Sons Ltd This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made. |
spellingShingle | Review Article Yu, Yang Yang, Jian Li, Quanpeng Xu, Boming Lian, Yifan Miao, Lin LINC00152: A pivotal oncogenic long non‐coding RNA in human cancers |
title |
LINC00152: A pivotal oncogenic long non‐coding RNA in human cancers |
title_full |
LINC00152: A pivotal oncogenic long non‐coding RNA in human cancers |
title_fullStr |
LINC00152: A pivotal oncogenic long non‐coding RNA in human cancers |
title_full_unstemmed |
LINC00152: A pivotal oncogenic long non‐coding RNA in human cancers |
title_short |
LINC00152: A pivotal oncogenic long non‐coding RNA in human cancers |
title_sort | linc00152: a pivotal oncogenic long non‐coding rna in human cancers |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6529135/ https://www.ncbi.nlm.nih.gov/pubmed/28464433 http://dx.doi.org/10.1111/cpr.12349 |
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