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Andrographolide attenuates bupivacaine-induced cytotoxicity in SH-SY5Y cells through preserving Akt/mTOR activity

Background: Bupivacaine (Bup) is the most commonly used local anesthetic. However, Bup induces cytotoxicity, especially in older patients. Recent reports have indicated that andrographolide (Andro) exhibits protective effects on human neurons. Nevertheless, whether Andro can inhibit Bup-induced cyto...

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Detalles Bibliográficos
Autores principales:	Zhang, Huiyuan, Wang, Weiwei, Du, Qian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2019
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6529178/ https://www.ncbi.nlm.nih.gov/pubmed/31190744 http://dx.doi.org/10.2147/DDDT.S201122

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