Population pharmacokinetics of inotuzumab ozogamicin in relapsed/refractory acute lymphoblastic leukemia and non-Hodgkin lymphoma

This population pharmacokinetics analysis evaluated the target-mediated drug disposition of inotuzumab ozogamicin (InO) through an empirical time-dependent clearance (CL(t)) term and identified potential covariates that may be important predictors of variability in InO distribution and elimination....

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Detalles Bibliográficos
Autores principales: Garrett, May, Ruiz-Garcia, Ana, Parivar, Kourosh, Hee, Brian, Boni, Joseph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2019
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6529376/
https://www.ncbi.nlm.nih.gov/pubmed/30859374
http://dx.doi.org/10.1007/s10928-018-9614-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6529376/
https://www.ncbi.nlm.nih.gov/pubmed/30859374
http://dx.doi.org/10.1007/s10928-018-9614-9

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