Cargando…

Expression profiling of immune inhibitory Siglecs and their ligands in patients with glioma

Gliomas appear to be highly immunosuppressive tumors, with a strong myeloid component. This includes MDSCs, which are a heterogeneous, immature myeloid cell population expressing myeloid markers Siglec-3 (CD33) and CD11b and lacking markers of mature myeloid cells including MHC II. Siglec-3 is a mem...

Descripción completa

Detalles Bibliográficos
Autores principales:	Santegoets, Kim C. M., Gielen, Paul R., Büll, Christian, Schulte, Barbara M., Kers-Rebel, Esther D., Küsters, Benno, Bossman, Sandra A. J. F. H., ter Laan, Mark, Wesseling, Pieter, Adema, Gosse J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2019
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6529385/ https://www.ncbi.nlm.nih.gov/pubmed/30953118 http://dx.doi.org/10.1007/s00262-019-02332-w

Ejemplares similares

Tumor cell-intrinsic and tumor microenvironmental conditions co-determine signaling by the glycoimmune checkpoint receptor Siglec-7
por: van Houtum, Eline J. H., et al.
Publicado: (2023)

Siglec Signaling in the Tumor Microenvironment
por: van Houtum, Eline J. H., et al.
Publicado: (2021)

Enterovirus-Infected β-Cells Induce Distinct Response Patterns in BDCA1(+) and BDCA3(+) Human Dendritic Cells
por: Schulte, Barbara M., et al.
Publicado: (2015)

Differential Susceptibility and Response of Primary Human Myeloid BDCA1(+) Dendritic Cells to Infection with Different Enteroviruses
por: Schulte, Barbara M., et al.
Publicado: (2013)

Potent Metabolic Sialylation Inhibitors Based on C-5-Modified Fluorinated Sialic Acids
por: Heise, Torben, et al.
Publicado: (2018)

Siglec Ligands
por: Gonzalez-Gil, Anabel, et al.
Publicado: (2021)

Glioma: experimental models and reality
por: Lenting, Krissie, et al.
Publicado: (2017)

Human brain sialoglycan ligand for CD33, a microglial inhibitory Siglec implicated in Alzheimer’s disease
por: Gonzalez-Gil, Anabel, et al.
Publicado: (2022)

Accuracy of Machine Learning Algorithms for the Classification of Molecular Features of Gliomas on MRI: A Systematic Literature Review and Meta-Analysis
por: van Kempen, Evi J., et al.
Publicado: (2021)

Recent Progress in the Methodologies to Identify Physiological Ligands of Siglecs
por: Jiang, Huei-Syuan, et al.
Publicado: (2021)

Sialic Acids on Tumor Cells Modulate IgA Therapy by Neutrophils via Inhibitory Receptors Siglec-7 and Siglec-9
por: Chan, Chilam, et al.
Publicado: (2023)

Siglec10—An immunosuppressor and negative predictor of survival prognosis in gliomas
por: Wang, Hesong, et al.
Publicado: (2022)

B Cell Siglecs–News on Signaling and Its Interplay With Ligand Binding
por: Meyer, Sarah J., et al.
Publicado: (2018)

Possible Influences of Endogenous and Exogenous Ligands on the Evolution of Human Siglecs
por: Angata, Takashi
Publicado: (2018)

MYC-driven synthesis of Siglec ligands is a glycoimmune checkpoint
por: Smith, Benjamin A. H., et al.
Publicado: (2023)

Potential Targeting of Siglecs, Mast Cell Inhibitory Receptors, in Interstitial Cystitis
por: Park, Chang-Shin, et al.
Publicado: (2011)

The inhibitory receptor Siglec‐G controls the severity of chronic lymphocytic leukemia
por: Röder, Bettina, et al.
Publicado: (2023)

Sialylated keratan sulfate proteoglycans are Siglec-8 ligands in human airways
por: Gonzalez-Gil, Anabel, et al.
Publicado: (2018)

Molecular cloning of porcine Siglec-3, Siglec-5 and Siglec-10, and identification of Siglec-10 as an alternative receptor for porcine reproductive and respiratory syndrome virus (PRRSV)
por: Xie, Jiexiong, et al.
Publicado: (2017)

Functional Inhibitory Siglec-6 Is Upregulated in Human Colorectal Cancer-Associated Mast Cells
por: Yu, Yingxin, et al.
Publicado: (2018)

A versatile soluble siglec scaffold for sensitive and quantitative detection of glycan ligands
por: Rodrigues, Emily, et al.
Publicado: (2020)

Cytokine and Chemokine Production by Human Pancreatic Islets Upon Enterovirus Infection
por: Schulte, Barbara M., et al.
Publicado: (2012)

HDAC inhibitors and immunotherapy; a double edged sword?
por: Kroesen, Michiel, et al.
Publicado: (2014)

Sialic acids in pancreatic cancer cells drive tumour-associated macrophage differentiation via the Siglec receptors Siglec-7 and Siglec-9
por: Rodriguez, Ernesto, et al.
Publicado: (2021)

Coevolution of Siglec-11 and Siglec-16 via gene conversion in primates
por: Hayakawa, Toshiyuki, et al.
Publicado: (2017)

Saponin-based adjuvants enhance antigen cross-presentation in human CD11c(+) CD1c(+) CD5(−) CD163(+) conventional type 2 dendritic cells
por: Ho, Nataschja I, et al.
Publicado: (2023)

Diffuse glioma growth: a guerilla war
por: Claes, An, et al.
Publicado: (2007)

Siglec-7/-9 ligands shield tumor cells from NK cell attack
por: Jandus, Camilla, et al.
Publicado: (2013)

Modulation of Siglec-7 Signaling Via In Situ-Created High-Affinity cis-Ligands
por: Hong, Senlian, et al.
Publicado: (2021)

Inhibitory Siglec-sialic acid interactions in balancing immunological activation and tolerance during viral infections
por: Saini, Pratima, et al.
Publicado: (2022)

Galactose 6-O-Sulfotransferases Are Not Required for the Generation of Siglec-F Ligands in Leukocytes or Lung Tissue
por: Patnode, Michael L., et al.
Publicado: (2013)

Molecular Basis and Role of Siglec-7 Ligand Expression on Chronic Lymphocytic Leukemia B Cells
por: Chang, Lan-Yi, et al.
Publicado: (2022)

Multifaceted effects of synthetic TLR2 ligand and Legionella pneumophilia on Treg-mediated suppression of T cell activation
por: van Maren, Wendy WC, et al.
Publicado: (2011)

Siglecs at the Host–Pathogen Interface
por: Chang, Yung-Chi, et al.
Publicado: (2020)

Siglecs as Therapeutic Targets in Cancer
por: Lim, Jackwee, et al.
Publicado: (2021)

Chronic OVA allergen challenged Siglec-F deficient mice have increased mucus, remodeling, and epithelial Siglec-F ligands which are up-regulated by IL-4 and IL-13
por: Cho, Jae Youn, et al.
Publicado: (2010)

The Roles of Siglec7 and Siglec9 on Natural Killer Cells in Virus Infection and Tumour Progression
por: Zheng, Yayun, et al.
Publicado: (2020)

Anti-GD2 mAb and Vorinostat synergize in the treatment of neuroblastoma
por: Kroesen, Michiel, et al.
Publicado: (2016)

Siglecs, Novel Immunotherapy Targets, Potentially Enhance The Effectiveness of Existing Immune Checkpoint Inhibitors in Glioma Immunotherapy
por: Li, Guan-Zhang, et al.
Publicado: (2019)

The Paired Siglecs in Brain Tumours Therapy: The Immunomodulatory Effect of Dexamethasone and Temozolomide in Human Glioma In Vitro Model
por: Wielgat, Przemyslaw, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_7kkirep13e4rffd7td5khaq600