Impaired cerebellar Purkinje cell potentiation generates unstable spatial map orientation and inaccurate navigation

Cerebellar activity supported by PKC-dependent long-term depression in Purkinje cells (PCs) is involved in the stabilization of self-motion based hippocampal representation, but the existence of cerebellar processes underlying integration of allocentric cues remains unclear. Using mutant-mice lackin...

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Detalles Bibliográficos
Autores principales: Lefort, Julie Marie, Vincent, Jean, Tallot, Lucille, Jarlier, Frédéric, De Zeeuw, Chris Innocentius, Rondi-Reig, Laure, Rochefort, Christelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6529420/
https://www.ncbi.nlm.nih.gov/pubmed/31113954
http://dx.doi.org/10.1038/s41467-019-09958-5

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