Central role of IP(3)R2-mediated Ca(2+) oscillation in self-renewal of liver cancer stem cells elucidated by high-signal ER sensor

Ca(2+) oscillation is a system-level property of the cellular Ca(2+)-handling machinery and encodes diverse physiological and pathological signals. The present study tests the hypothesis that Ca(2+) oscillations play a vital role in maintaining the stemness of liver cancer stem cells (CSCs), which a...

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Detalles Bibliográficos
Autores principales: Sun, Cuiwei, Shui, Bo, Zhao, Wei, Liu, Hui, Li, Wenwen, Lee, Jane C., Doran, Robert, Lee, Frank K., Sun, Tao, Shen, Qing Sunny, Wang, Xianhua, Reining, Shaun, Kotlikoff, Michael I., Zhang, Zhiqian, Cheng, Heping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6529459/
https://www.ncbi.nlm.nih.gov/pubmed/31113961
http://dx.doi.org/10.1038/s41419-019-1613-2

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