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Adjacent intact nociceptive neurons drive the acute outburst of pain following peripheral axotomy
Injury of peripheral nerves may quickly induce severe pain, but the mechanism remains obscure. We observed a rapid onset of spontaneous pain and evoked pain hypersensitivity after acute transection of the L5 spinal nerve (SNT) in awake rats. The outburst of pain was associated with a rapid developme...
Autores principales: | Chen, Zhiyong, Wang, Tao, Fang, Yehong, Luo, Dan, Anderson, Michael, Huang, Qian, He, Shaoqiu, Song, Xiaodan, Cui, Huan, Dong, Xinzhong, Xie, Yikuan, Guan, Yun, Ma, Chao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6529466/ https://www.ncbi.nlm.nih.gov/pubmed/31113988 http://dx.doi.org/10.1038/s41598-019-44172-9 |
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