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Methyl-β-cyclodextrin, an actin depolymerizer augments the antiproliferative potential of microtubule-targeting agents

Methyl-β-cyclodextrin (MCD), an established pharmacological excipient, depolymerizes the actin cytoskeleton. In this work, we investigated the effect of MCD-mediated actin depolymerization on various cellular phenotypes including traction force, cell stiffness, focal adhesions, and intracellular dru...

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Detalles Bibliográficos
Autores principales:	Mundhara, Nikita, Majumder, Abhijit, Panda, Dulal
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6529501/ https://www.ncbi.nlm.nih.gov/pubmed/31113967 http://dx.doi.org/10.1038/s41598-019-43947-4

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