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Clinical features and outcomes of tetanus: a retrospective study

Background: Tetanus is a serious disease resulting in muscle spasm, and even death. Methods: A retrospective, single-center study was conducted by analyzing demographic and clinical parameters. Results: The study included 12 males (70.6%) and 5 females (29.4%). The mean age of the patients was 56.71...

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Autores principales: Fan, Zhe, Zhao, Yue, Wang, Shuang, Zhang, Feng, Zhuang, Chengjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6529615/
https://www.ncbi.nlm.nih.gov/pubmed/31190917
http://dx.doi.org/10.2147/IDR.S204650
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author Fan, Zhe
Zhao, Yue
Wang, Shuang
Zhang, Feng
Zhuang, Chengjun
author_facet Fan, Zhe
Zhao, Yue
Wang, Shuang
Zhang, Feng
Zhuang, Chengjun
author_sort Fan, Zhe
collection PubMed
description Background: Tetanus is a serious disease resulting in muscle spasm, and even death. Methods: A retrospective, single-center study was conducted by analyzing demographic and clinical parameters. Results: The study included 12 males (70.6%) and 5 females (29.4%). The mean age of the patients was 56.71±9.05 years. Patient occupations included farming (47.0%), retired (23.5), homebound (23.5), and workers (6.0%). The causes of patient injuries were as follows: metal injury (52.9%), deep injury (29.4%), electrical injury (5.9%), maxillofacial region and knee injury (5.9%), and skin ulceration (5.9%). The disease duration ranged from 3 to 36 days, and the mean incubation period was 12.65±10.17 days. Four patients had co-morbidities. The infected patients were given tetanus antitoxin (TAT) and antibiotics treatment. One patient was given continuous renal replacement therapy (CRRT) and only one patient died. Conclusions: In our department, although tetanus is a serious disease, with effective treatment, patients have reasonable cure and low death rates.
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spelling pubmed-65296152019-06-12 Clinical features and outcomes of tetanus: a retrospective study Fan, Zhe Zhao, Yue Wang, Shuang Zhang, Feng Zhuang, Chengjun Infect Drug Resist Original Research Background: Tetanus is a serious disease resulting in muscle spasm, and even death. Methods: A retrospective, single-center study was conducted by analyzing demographic and clinical parameters. Results: The study included 12 males (70.6%) and 5 females (29.4%). The mean age of the patients was 56.71±9.05 years. Patient occupations included farming (47.0%), retired (23.5), homebound (23.5), and workers (6.0%). The causes of patient injuries were as follows: metal injury (52.9%), deep injury (29.4%), electrical injury (5.9%), maxillofacial region and knee injury (5.9%), and skin ulceration (5.9%). The disease duration ranged from 3 to 36 days, and the mean incubation period was 12.65±10.17 days. Four patients had co-morbidities. The infected patients were given tetanus antitoxin (TAT) and antibiotics treatment. One patient was given continuous renal replacement therapy (CRRT) and only one patient died. Conclusions: In our department, although tetanus is a serious disease, with effective treatment, patients have reasonable cure and low death rates. Dove 2019-05-16 /pmc/articles/PMC6529615/ /pubmed/31190917 http://dx.doi.org/10.2147/IDR.S204650 Text en © 2019 Fan et al. http://creativecommons.org/licenses/by-nc/3.0/ This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
spellingShingle Original Research
Fan, Zhe
Zhao, Yue
Wang, Shuang
Zhang, Feng
Zhuang, Chengjun
Clinical features and outcomes of tetanus: a retrospective study
title Clinical features and outcomes of tetanus: a retrospective study
title_full Clinical features and outcomes of tetanus: a retrospective study
title_fullStr Clinical features and outcomes of tetanus: a retrospective study
title_full_unstemmed Clinical features and outcomes of tetanus: a retrospective study
title_short Clinical features and outcomes of tetanus: a retrospective study
title_sort clinical features and outcomes of tetanus: a retrospective study
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6529615/
https://www.ncbi.nlm.nih.gov/pubmed/31190917
http://dx.doi.org/10.2147/IDR.S204650
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