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Herpes Simplex Virus 1 Tegument Protein UL46 Inhibits TANK-Binding Kinase 1-Mediated Signaling

TANK-binding kinase 1 (TBK1) is a key component of the antiviral immunity signaling pathway. It activates downstream interferon regulatory factor 3 (IRF3) and subsequent type I interferon (IFN-I) production. Herpes simplex virus type 1 (HSV-1) can antagonize host antiviral immune responses and lead...

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Detalles Bibliográficos
Autores principales:	You, Hongjuan, Zheng, Sisilia, Huang, Zhiming, Lin, Yingying, Shen, Qingtang, Zheng, Chunfu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6529639/ https://www.ncbi.nlm.nih.gov/pubmed/31113902 http://dx.doi.org/10.1128/mBio.00919-19

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