Rapid detection of bacille Calmette-Guérin-associated mycotic aortic aneurysm using novel cell-free DNA assay

Intravesical instillation of bacille Calmette-Guérin (BCG), an attenuated strain of Mycobacterium bovis, is an adjuvant immunotherapy for bladder carcinoma. Typical complications include fever, malaise, and dysuria. However, more severe complications have been reported, including granulomatous pneum...

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Detalles Bibliográficos
Autores principales: Vudatha, Vignesh, Ranson, Mark, Blair, Lily, Ahmed, Asim A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Vascular infection
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6529677/
https://www.ncbi.nlm.nih.gov/pubmed/31193416
http://dx.doi.org/10.1016/j.jvscit.2018.11.006
Descripción
Sumario:Intravesical instillation of bacille Calmette-Guérin (BCG), an attenuated strain of Mycobacterium bovis, is an adjuvant immunotherapy for bladder carcinoma. Typical complications include fever, malaise, and dysuria. However, more severe complications have been reported, including granulomatous pneumonitis, BCG sepsis, and vascular infections. We present a case of an infrarenal abdominal aortic aneurysm complicated by iliopsoas abscess 2 years after BCG treatment and discuss a novel diagnostic tool for mycobacterial strain identification.

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