Cargando…

Rapid detection of bacille Calmette-Guérin-associated mycotic aortic aneurysm using novel cell-free DNA assay

Intravesical instillation of bacille Calmette-Guérin (BCG), an attenuated strain of Mycobacterium bovis, is an adjuvant immunotherapy for bladder carcinoma. Typical complications include fever, malaise, and dysuria. However, more severe complications have been reported, including granulomatous pneum...

Descripción completa

Detalles Bibliográficos
Autores principales: Vudatha, Vignesh, Ranson, Mark, Blair, Lily, Ahmed, Asim A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6529677/
https://www.ncbi.nlm.nih.gov/pubmed/31193416
http://dx.doi.org/10.1016/j.jvscit.2018.11.006
_version_ 1783420450502606848
author Vudatha, Vignesh
Ranson, Mark
Blair, Lily
Ahmed, Asim A.
author_facet Vudatha, Vignesh
Ranson, Mark
Blair, Lily
Ahmed, Asim A.
author_sort Vudatha, Vignesh
collection PubMed
description Intravesical instillation of bacille Calmette-Guérin (BCG), an attenuated strain of Mycobacterium bovis, is an adjuvant immunotherapy for bladder carcinoma. Typical complications include fever, malaise, and dysuria. However, more severe complications have been reported, including granulomatous pneumonitis, BCG sepsis, and vascular infections. We present a case of an infrarenal abdominal aortic aneurysm complicated by iliopsoas abscess 2 years after BCG treatment and discuss a novel diagnostic tool for mycobacterial strain identification.
format Online
Article
Text
id pubmed-6529677
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher Elsevier
record_format MEDLINE/PubMed
spelling pubmed-65296772019-05-28 Rapid detection of bacille Calmette-Guérin-associated mycotic aortic aneurysm using novel cell-free DNA assay Vudatha, Vignesh Ranson, Mark Blair, Lily Ahmed, Asim A. J Vasc Surg Cases Innov Tech Vascular infection Intravesical instillation of bacille Calmette-Guérin (BCG), an attenuated strain of Mycobacterium bovis, is an adjuvant immunotherapy for bladder carcinoma. Typical complications include fever, malaise, and dysuria. However, more severe complications have been reported, including granulomatous pneumonitis, BCG sepsis, and vascular infections. We present a case of an infrarenal abdominal aortic aneurysm complicated by iliopsoas abscess 2 years after BCG treatment and discuss a novel diagnostic tool for mycobacterial strain identification. Elsevier 2019-04-28 /pmc/articles/PMC6529677/ /pubmed/31193416 http://dx.doi.org/10.1016/j.jvscit.2018.11.006 Text en © 2019 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Vascular infection
Vudatha, Vignesh
Ranson, Mark
Blair, Lily
Ahmed, Asim A.
Rapid detection of bacille Calmette-Guérin-associated mycotic aortic aneurysm using novel cell-free DNA assay
title Rapid detection of bacille Calmette-Guérin-associated mycotic aortic aneurysm using novel cell-free DNA assay
title_full Rapid detection of bacille Calmette-Guérin-associated mycotic aortic aneurysm using novel cell-free DNA assay
title_fullStr Rapid detection of bacille Calmette-Guérin-associated mycotic aortic aneurysm using novel cell-free DNA assay
title_full_unstemmed Rapid detection of bacille Calmette-Guérin-associated mycotic aortic aneurysm using novel cell-free DNA assay
title_short Rapid detection of bacille Calmette-Guérin-associated mycotic aortic aneurysm using novel cell-free DNA assay
title_sort rapid detection of bacille calmette-guérin-associated mycotic aortic aneurysm using novel cell-free dna assay
topic Vascular infection
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6529677/
https://www.ncbi.nlm.nih.gov/pubmed/31193416
http://dx.doi.org/10.1016/j.jvscit.2018.11.006
work_keys_str_mv AT vudathavignesh rapiddetectionofbacillecalmetteguerinassociatedmycoticaorticaneurysmusingnovelcellfreednaassay
AT ransonmark rapiddetectionofbacillecalmetteguerinassociatedmycoticaorticaneurysmusingnovelcellfreednaassay
AT blairlily rapiddetectionofbacillecalmetteguerinassociatedmycoticaorticaneurysmusingnovelcellfreednaassay
AT ahmedasima rapiddetectionofbacillecalmetteguerinassociatedmycoticaorticaneurysmusingnovelcellfreednaassay