STING-IRF3 contributes to lipopolysaccharide-induced cardiac dysfunction, inflammation, apoptosis and pyroptosis by activating NLRP3

Mountainous evidence suggests that inflammation, cardiomyocyte apoptosis and pyroptosis are involved in the development of sepsis and sepsis-induced cardiomyopathy (SIC). Stimulator of interferon genes (STING) is an indispensable molecule that could regulate inflammation and immune response in multi...

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Detalles Bibliográficos
Autores principales: Li, Ning, Zhou, Heng, Wu, Haiming, Wu, Qingqing, Duan, Mingxia, Deng, Wei, Tang, Qizhu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6529775/
https://www.ncbi.nlm.nih.gov/pubmed/31121492
http://dx.doi.org/10.1016/j.redox.2019.101215

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