Red Blood Cell Homeostasis and Altered Vesicle Formation in Patients With Paroxysmal Nocturnal Hemoglobinuria

A subset of the red blood cells (RBCs) of patients with paroxysmal nocturnal hemoglobinuria (PNH) lacks GPI-anchored proteins. Some of these proteins, such as CD59, inhibit complement activation and protect against complement-mediated lysis. This pathology thus provides the possibility to explore th...

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Detalles Bibliográficos
Autores principales: Freitas Leal, Joames K., Preijers, Frank, Brock, Roland, Adjobo-Hermans, Merel, Bosman, Giel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6529780/
https://www.ncbi.nlm.nih.gov/pubmed/31156458
http://dx.doi.org/10.3389/fphys.2019.00578

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