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Are There Common Mechanisms Between the Hutchinson–Gilford Progeria Syndrome and Natural Aging?
The Hutchinson–Gilford progeria syndrome (HGPS) is a premature aging disease caused by mutations of the LMNA gene leading to increased production of a partially processed form of the nuclear fibrillar protein lamin A – progerin. Progerin acts as a dominant factor that leads to multiple morphological...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6529819/ https://www.ncbi.nlm.nih.gov/pubmed/31156709 http://dx.doi.org/10.3389/fgene.2019.00455 |