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Testicular Cancer—Surgical Treatment

Testicular Germ Cell Tumor (GCT) is the most common solid tumor in men between the ages of 20–44. Men diagnosed with GCT have excellent survival rates due to advances in the multimodal treatment paradigm of chemotherapy, radiation therapy, and surgery. When considering the adequate treatment, severa...

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Autores principales: Vaz, Rodrigo Markus, Bordenali, Gustavo, Bibancos, Mauro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6529845/
https://www.ncbi.nlm.nih.gov/pubmed/31156556
http://dx.doi.org/10.3389/fendo.2019.00308
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author Vaz, Rodrigo Markus
Bordenali, Gustavo
Bibancos, Mauro
author_facet Vaz, Rodrigo Markus
Bordenali, Gustavo
Bibancos, Mauro
author_sort Vaz, Rodrigo Markus
collection PubMed
description Testicular Germ Cell Tumor (GCT) is the most common solid tumor in men between the ages of 20–44. Men diagnosed with GCT have excellent survival rates due to advances in the multimodal treatment paradigm of chemotherapy, radiation therapy, and surgery. When considering the adequate treatment, several variables should be investigated and known to select the proper procedure. Therefore, when considering Testicular Intra-Epithelial Neoplasia, organ-sparring treatment, such as radiotherapy or organ-sparring surgery should be considered, reaching a cure rate of 98%. However, when the case is of a seminoma or a non-seminoma, orchiectomy is usually the chosen procedure, reaching an oncological cure rate of 80–85%, when there is no metastasis. Retroperitoneal Lymph Node Dissection (RPLND) is generally considered as a treatment option for non-seminomas, when lymph nodes are compromised. There are three different RPLND techniques: open, laparoscopic, and robotic. The open approach is as effective as the other two in its oncological efficiency. Although, when considering both laparoscopic and robotic approach, hospital stays are significantly reduced, better cosmetic results, and less complications when compared to the open approach. Both laparoscopic and robotic approaches require extensive experience and have a steep learning curve, while also providing similar outcome, however, recent studies have been pointing out a slight increase of advantages on the robotic approach. Therefore, further studies are necessary to assert the robotic approach superiority. Also, it is noteworthy that new technologies are on the rise, improving the laparoscopic approach, requiring further studies after their uses are consolidated.
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spelling pubmed-65298452019-05-31 Testicular Cancer—Surgical Treatment Vaz, Rodrigo Markus Bordenali, Gustavo Bibancos, Mauro Front Endocrinol (Lausanne) Endocrinology Testicular Germ Cell Tumor (GCT) is the most common solid tumor in men between the ages of 20–44. Men diagnosed with GCT have excellent survival rates due to advances in the multimodal treatment paradigm of chemotherapy, radiation therapy, and surgery. When considering the adequate treatment, several variables should be investigated and known to select the proper procedure. Therefore, when considering Testicular Intra-Epithelial Neoplasia, organ-sparring treatment, such as radiotherapy or organ-sparring surgery should be considered, reaching a cure rate of 98%. However, when the case is of a seminoma or a non-seminoma, orchiectomy is usually the chosen procedure, reaching an oncological cure rate of 80–85%, when there is no metastasis. Retroperitoneal Lymph Node Dissection (RPLND) is generally considered as a treatment option for non-seminomas, when lymph nodes are compromised. There are three different RPLND techniques: open, laparoscopic, and robotic. The open approach is as effective as the other two in its oncological efficiency. Although, when considering both laparoscopic and robotic approach, hospital stays are significantly reduced, better cosmetic results, and less complications when compared to the open approach. Both laparoscopic and robotic approaches require extensive experience and have a steep learning curve, while also providing similar outcome, however, recent studies have been pointing out a slight increase of advantages on the robotic approach. Therefore, further studies are necessary to assert the robotic approach superiority. Also, it is noteworthy that new technologies are on the rise, improving the laparoscopic approach, requiring further studies after their uses are consolidated. Frontiers Media S.A. 2019-05-15 /pmc/articles/PMC6529845/ /pubmed/31156556 http://dx.doi.org/10.3389/fendo.2019.00308 Text en Copyright © 2019 Vaz, Bordenali and Bibancos. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Endocrinology
Vaz, Rodrigo Markus
Bordenali, Gustavo
Bibancos, Mauro
Testicular Cancer—Surgical Treatment
title Testicular Cancer—Surgical Treatment
title_full Testicular Cancer—Surgical Treatment
title_fullStr Testicular Cancer—Surgical Treatment
title_full_unstemmed Testicular Cancer—Surgical Treatment
title_short Testicular Cancer—Surgical Treatment
title_sort testicular cancer—surgical treatment
topic Endocrinology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6529845/
https://www.ncbi.nlm.nih.gov/pubmed/31156556
http://dx.doi.org/10.3389/fendo.2019.00308
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