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PARP1 Inhibition as a Novel Therapeutic Target for Keloid Disease

Objective: Inactivation of poly(ADP-ribose) polymerase 1 (PARP1) has been found to have protective effect in several fibrotic diseases. But the effect is not studied yet in keloids. Herein, we evaluated the therapeutic effect of PARP1 inhibitor, rucaparib, for keloids. Approach: The protein expressi...

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Detalles Bibliográficos
Autores principales:	Park, Tae Hwan, Kim, Chan Woo, Choi, Jin Sik, Park, Yun Joo, Chong, Yosep, Park, Min Ji, Cho, Yuri
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Mary Ann Liebert, Inc., publishers 2019
Materias:	Discovery Express
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6529855/ https://www.ncbi.nlm.nih.gov/pubmed/31119062 http://dx.doi.org/10.1089/wound.2018.0910

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