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Induction of β-adrenergic metaplasticity of LTP requires intact anchoring of PKA
Beta-adrenergic receptors (β-ARs) prime hippocampal synapses to stabilize long-term potentiation (LTP). This “metaplasticity” can persist for 1–2 h after pharmacologic activation of β-ARs. It requires activation of PKA (cAMP-dependent protein kinase) during β-AR priming. A-kinase anchoring proteins...
Autores principales: | Hoffman, Janlyn R., Brandwein, Nathan J., Nguyen, Peter V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6529881/ https://www.ncbi.nlm.nih.gov/pubmed/31109969 http://dx.doi.org/10.1101/lm.049635.119 |
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