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Induction of β-adrenergic metaplasticity of LTP requires intact anchoring of PKA

Beta-adrenergic receptors (β-ARs) prime hippocampal synapses to stabilize long-term potentiation (LTP). This “metaplasticity” can persist for 1–2 h after pharmacologic activation of β-ARs. It requires activation of PKA (cAMP-dependent protein kinase) during β-AR priming. A-kinase anchoring proteins...

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Detalles Bibliográficos
Autores principales: Hoffman, Janlyn R., Brandwein, Nathan J., Nguyen, Peter V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6529881/
https://www.ncbi.nlm.nih.gov/pubmed/31109969
http://dx.doi.org/10.1101/lm.049635.119

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