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Protection against pressure overload-induced right heart failure by uncoupling protein 2 silencing

AIMS: The role of uncoupling protein 2 (UCP2) in cardiac adaptation to pressure overload remains unclear. In a classical model of left ventricular pressure overload genetic deletion of UCP2 (UCP2(−/−)) protected against cardiac hypertrophy and failure. However, in UCP2(−/−) mice increased proliferat...

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Detalles Bibliográficos
Autores principales:	Esfandiary, Azadeh, Kutsche, Hanna S, Schreckenberg, Rolf, Weber, Martin, Pak, Oleg, Kojonazarov, Baktybek, Sydykov, Akylbek, Hirschhäuser, Christine, Wolf, Annemarie, Haag, Daniela, Hecker, Matthias, Fink, Ludger, Seeger, Werner, Ghofrani, Hossein A, Schermuly, Ralph T, Weißmann, Norbert, Schulz, Rainer, Rohrbach, Susanne, Li, Ling, Sommer, Natascha, Schlüter, Klaus-Dieter
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2019
Materias:	Spotlight Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6529920/ https://www.ncbi.nlm.nih.gov/pubmed/30850841 http://dx.doi.org/10.1093/cvr/cvz049

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