Cargando…
Cognitive deficits in adult m.3243A>G‐ and m.8344A>G‐related mitochondrial disease: importance of correcting for baseline intellectual ability
OBJECTIVE: To determine the cognitive profile of adult patients with mitochondrial disease, and the effect of disease severity on cognition. METHODS: Using a prospective case‐control design, we compared cognition of patients to normative data and to matched controls, assessed three times over 18 mon...
Autores principales: | Moore, Heather L., Kelly, Thomas, Bright, Alexandra, Field, Robert H., Schaefer, Andrew M., Blain, Alasdair P., Taylor, Robert W., McFarland, Robert, Turnbull, Doug M., Gorman, Gráinne S. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6529924/ https://www.ncbi.nlm.nih.gov/pubmed/31139680 http://dx.doi.org/10.1002/acn3.736 |
Ejemplares similares
-
Discrete gait characteristics are associated with m.3243A>G and m.8344A>G variants of mitochondrial disease and its pathological consequences
por: Galna, Brook, et al.
Publicado: (2013) -
Phenotypic heterogeneity in m.3243A>G mitochondrial disease: The role of nuclear factors
por: Pickett, Sarah J., et al.
Publicado: (2018) -
Distal weakness with respiratory insufficiency caused by the m.8344A > G “MERRF” mutation
por: Blakely, Emma L., et al.
Publicado: (2014) -
mtDNA heteroplasmy level and copy number indicate disease burden in m.3243A>G mitochondrial disease
por: Grady, John P, et al.
Publicado: (2018) -
Cardiomyopathy is common in patients with the mitochondrial DNA m.3243A>G mutation and correlates with mutation load
por: Hollingsworth, Kieren G., et al.
Publicado: (2012)