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Linking aberrant chromatin features in chronic lymphocytic leukemia to transcription factor networks
In chronic lymphocytic leukemia (CLL), a diverse set of genetic mutations is embedded in a deregulated epigenetic landscape that drives cancerogenesis. To elucidate the role of aberrant chromatin features, we mapped DNA methylation, seven histone modifications, nucleosome positions, chromatin access...
Autores principales: | Mallm, Jan‐Philipp, Iskar, Murat, Ishaque, Naveed, Klett, Lara C, Kugler, Sabrina J, Muino, Jose M, Teif, Vladimir B, Poos, Alexandra M, Großmann, Sebastian, Erdel, Fabian, Tavernari, Daniele, Koser, Sandra D, Schumacher, Sabrina, Brors, Benedikt, König, Rainer, Remondini, Daniel, Vingron, Martin, Stilgenbauer, Stephan, Lichter, Peter, Zapatka, Marc, Mertens, Daniel, Rippe, Karsten |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6529931/ https://www.ncbi.nlm.nih.gov/pubmed/31118277 http://dx.doi.org/10.15252/msb.20188339 |
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