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Optimal management of malignant left-sided large bowel obstruction: do international guidelines agree?

BACKGROUND: Approximately 20% of patients diagnosed with colorectal cancer will present with left-sided large bowel obstruction. The optimal management of this cohort of patients remains unclear. We aimed to review international guidelines to see if there was a consensus on the treatment of this sur...

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Autores principales: Webster, Peter John, Aldoori, Joanna, Burke, Dermot Anthony
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6530001/
https://www.ncbi.nlm.nih.gov/pubmed/31139245
http://dx.doi.org/10.1186/s13017-019-0242-5
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author Webster, Peter John
Aldoori, Joanna
Burke, Dermot Anthony
author_facet Webster, Peter John
Aldoori, Joanna
Burke, Dermot Anthony
author_sort Webster, Peter John
collection PubMed
description BACKGROUND: Approximately 20% of patients diagnosed with colorectal cancer will present with left-sided large bowel obstruction. The optimal management of this cohort of patients remains unclear. We aimed to review international guidelines to see if there was a consensus on the treatment of this surgical emergency. METHODS: The PubMed and Medline databases were searched for guidelines on the management of left-sided, malignant large bowel obstruction (MBO) between 2010 and 2018. RESULTS: Nineteen guidelines were identified spanning a range of continents. There was no clear consensus on the management of potentially resectable disease. Eight guidelines (42%) suggested primary surgery, two guidelines (11%) suggested stenting as a bridge to surgery and nine guidelines (47%) suggested surgery or stenting could be performed. Primary resection with or without anastomosis was the most frequently recommended procedure (n = 6 35%), but over a third of guidelines gave no operative recommendations. There was very limited detail on the stenting procedure and how long elective surgery should be deferred. In the palliative situation, there was general agreement that stents should be offered in preference to surgery. CONCLUSION: International guidelines offer limited and contrasting recommendations on the management of left-sided MBO. There is a lack of high-quality evidence to support whether emergency surgery or stenting as a bridge to surgery is the optimal procedure in terms of morbidity, mortality and long-term oncological outcome.
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spelling pubmed-65300012019-05-28 Optimal management of malignant left-sided large bowel obstruction: do international guidelines agree? Webster, Peter John Aldoori, Joanna Burke, Dermot Anthony World J Emerg Surg Review BACKGROUND: Approximately 20% of patients diagnosed with colorectal cancer will present with left-sided large bowel obstruction. The optimal management of this cohort of patients remains unclear. We aimed to review international guidelines to see if there was a consensus on the treatment of this surgical emergency. METHODS: The PubMed and Medline databases were searched for guidelines on the management of left-sided, malignant large bowel obstruction (MBO) between 2010 and 2018. RESULTS: Nineteen guidelines were identified spanning a range of continents. There was no clear consensus on the management of potentially resectable disease. Eight guidelines (42%) suggested primary surgery, two guidelines (11%) suggested stenting as a bridge to surgery and nine guidelines (47%) suggested surgery or stenting could be performed. Primary resection with or without anastomosis was the most frequently recommended procedure (n = 6 35%), but over a third of guidelines gave no operative recommendations. There was very limited detail on the stenting procedure and how long elective surgery should be deferred. In the palliative situation, there was general agreement that stents should be offered in preference to surgery. CONCLUSION: International guidelines offer limited and contrasting recommendations on the management of left-sided MBO. There is a lack of high-quality evidence to support whether emergency surgery or stenting as a bridge to surgery is the optimal procedure in terms of morbidity, mortality and long-term oncological outcome. BioMed Central 2019-05-22 /pmc/articles/PMC6530001/ /pubmed/31139245 http://dx.doi.org/10.1186/s13017-019-0242-5 Text en © The Author(s). 2019 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Review
Webster, Peter John
Aldoori, Joanna
Burke, Dermot Anthony
Optimal management of malignant left-sided large bowel obstruction: do international guidelines agree?
title Optimal management of malignant left-sided large bowel obstruction: do international guidelines agree?
title_full Optimal management of malignant left-sided large bowel obstruction: do international guidelines agree?
title_fullStr Optimal management of malignant left-sided large bowel obstruction: do international guidelines agree?
title_full_unstemmed Optimal management of malignant left-sided large bowel obstruction: do international guidelines agree?
title_short Optimal management of malignant left-sided large bowel obstruction: do international guidelines agree?
title_sort optimal management of malignant left-sided large bowel obstruction: do international guidelines agree?
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6530001/
https://www.ncbi.nlm.nih.gov/pubmed/31139245
http://dx.doi.org/10.1186/s13017-019-0242-5
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