Apolipoprotein-J blocks increased cell injury elicited by ox-LDL via inhibiting ROS-CaMKII pathway

BACKGROUND: Oxidized low-density lipoprotein (ox-LDL) is crucial in cardiac injury. Apolipoprotein-J (ApoJ) contributes to antiapoptotic effects in the heart. We aimed to evaluate the protective effects of ApoJ against ox-LDL cytotoxicity in Neonatal rat ventricular cells (NRVCs). METHODS AND RESULT...

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Detalles Bibliográficos
Autores principales: Ma, Yanzhuo, Gong, Zhi, Nan, Kai, Qi, Shuying, Chen, Yu, Ding, Chao, Wang, Dongmei, Ru, Leisheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6530009/
https://www.ncbi.nlm.nih.gov/pubmed/31113434
http://dx.doi.org/10.1186/s12944-019-1066-8

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