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Novel anti-CD38 humanized mAb SG003 possessed enhanced cytotoxicity in lymphoma than Daratumumab via antibody-dependent cell-mediated cytotoxicity

BACKGROUND: In vivo use of monoclonal antibodies has become routine clinical practice in the treatment of human cancer. CD38 is an attractive target, because it has double roles, as a receptor and an ectoenzyme. Daratumumab, an anti-CD38 antibody, is currently in the clinical trials for multiple mye...

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Detalles Bibliográficos
Autores principales:	Yu, Tao, Qiao, Chunxia, Lv, Ming, Tang, Luqun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6530185/ https://www.ncbi.nlm.nih.gov/pubmed/31118070 http://dx.doi.org/10.1186/s12896-019-0524-8

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