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Recent advances in understanding Candida albicans hyphal growth

Morphological changes are critical for the virulence of a range of plant and human fungal pathogens. Candida albicans is a major human fungal pathogen whose ability to switch between different morphological states is associated with its adaptability and pathogenicity. In particular, C. albicans can...

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Autores principales: Arkowitz, Robert A., Bassilana, Martine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6530606/
https://www.ncbi.nlm.nih.gov/pubmed/31131089
http://dx.doi.org/10.12688/f1000research.18546.1
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author Arkowitz, Robert A.
Bassilana, Martine
author_facet Arkowitz, Robert A.
Bassilana, Martine
author_sort Arkowitz, Robert A.
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description Morphological changes are critical for the virulence of a range of plant and human fungal pathogens. Candida albicans is a major human fungal pathogen whose ability to switch between different morphological states is associated with its adaptability and pathogenicity. In particular, C. albicans can switch from an oval yeast form to a filamentous hyphal form, which is characteristic of filamentous fungi. What mechanisms underlie hyphal growth and how are they affected by environmental stimuli from the host or resident microbiota? These questions are the focus of intensive research, as understanding C. albicans hyphal growth has broad implications for cell biological and medical research.
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spelling pubmed-65306062019-05-24 Recent advances in understanding Candida albicans hyphal growth Arkowitz, Robert A. Bassilana, Martine F1000Res Review Morphological changes are critical for the virulence of a range of plant and human fungal pathogens. Candida albicans is a major human fungal pathogen whose ability to switch between different morphological states is associated with its adaptability and pathogenicity. In particular, C. albicans can switch from an oval yeast form to a filamentous hyphal form, which is characteristic of filamentous fungi. What mechanisms underlie hyphal growth and how are they affected by environmental stimuli from the host or resident microbiota? These questions are the focus of intensive research, as understanding C. albicans hyphal growth has broad implications for cell biological and medical research. F1000 Research Limited 2019-05-21 /pmc/articles/PMC6530606/ /pubmed/31131089 http://dx.doi.org/10.12688/f1000research.18546.1 Text en Copyright: © 2019 Arkowitz RA and Bassilana M http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review
Arkowitz, Robert A.
Bassilana, Martine
Recent advances in understanding Candida albicans hyphal growth
title Recent advances in understanding Candida albicans hyphal growth
title_full Recent advances in understanding Candida albicans hyphal growth
title_fullStr Recent advances in understanding Candida albicans hyphal growth
title_full_unstemmed Recent advances in understanding Candida albicans hyphal growth
title_short Recent advances in understanding Candida albicans hyphal growth
title_sort recent advances in understanding candida albicans hyphal growth
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6530606/
https://www.ncbi.nlm.nih.gov/pubmed/31131089
http://dx.doi.org/10.12688/f1000research.18546.1
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