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Recent advances in understanding Candida albicans hyphal growth
Morphological changes are critical for the virulence of a range of plant and human fungal pathogens. Candida albicans is a major human fungal pathogen whose ability to switch between different morphological states is associated with its adaptability and pathogenicity. In particular, C. albicans can...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
F1000 Research Limited
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6530606/ https://www.ncbi.nlm.nih.gov/pubmed/31131089 http://dx.doi.org/10.12688/f1000research.18546.1 |
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author | Arkowitz, Robert A. Bassilana, Martine |
author_facet | Arkowitz, Robert A. Bassilana, Martine |
author_sort | Arkowitz, Robert A. |
collection | PubMed |
description | Morphological changes are critical for the virulence of a range of plant and human fungal pathogens. Candida albicans is a major human fungal pathogen whose ability to switch between different morphological states is associated with its adaptability and pathogenicity. In particular, C. albicans can switch from an oval yeast form to a filamentous hyphal form, which is characteristic of filamentous fungi. What mechanisms underlie hyphal growth and how are they affected by environmental stimuli from the host or resident microbiota? These questions are the focus of intensive research, as understanding C. albicans hyphal growth has broad implications for cell biological and medical research. |
format | Online Article Text |
id | pubmed-6530606 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | F1000 Research Limited |
record_format | MEDLINE/PubMed |
spelling | pubmed-65306062019-05-24 Recent advances in understanding Candida albicans hyphal growth Arkowitz, Robert A. Bassilana, Martine F1000Res Review Morphological changes are critical for the virulence of a range of plant and human fungal pathogens. Candida albicans is a major human fungal pathogen whose ability to switch between different morphological states is associated with its adaptability and pathogenicity. In particular, C. albicans can switch from an oval yeast form to a filamentous hyphal form, which is characteristic of filamentous fungi. What mechanisms underlie hyphal growth and how are they affected by environmental stimuli from the host or resident microbiota? These questions are the focus of intensive research, as understanding C. albicans hyphal growth has broad implications for cell biological and medical research. F1000 Research Limited 2019-05-21 /pmc/articles/PMC6530606/ /pubmed/31131089 http://dx.doi.org/10.12688/f1000research.18546.1 Text en Copyright: © 2019 Arkowitz RA and Bassilana M http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Arkowitz, Robert A. Bassilana, Martine Recent advances in understanding Candida albicans hyphal growth |
title | Recent advances in understanding
Candida albicans hyphal growth |
title_full | Recent advances in understanding
Candida albicans hyphal growth |
title_fullStr | Recent advances in understanding
Candida albicans hyphal growth |
title_full_unstemmed | Recent advances in understanding
Candida albicans hyphal growth |
title_short | Recent advances in understanding
Candida albicans hyphal growth |
title_sort | recent advances in understanding
candida albicans hyphal growth |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6530606/ https://www.ncbi.nlm.nih.gov/pubmed/31131089 http://dx.doi.org/10.12688/f1000research.18546.1 |
work_keys_str_mv | AT arkowitzroberta recentadvancesinunderstandingcandidaalbicanshyphalgrowth AT bassilanamartine recentadvancesinunderstandingcandidaalbicanshyphalgrowth |