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Aloe-emodin Attenuates Staphylococcus aureus Pathogenicity by Interfering With the Oligomerization of α-Toxin

α-toxin, an essential virulence factor secreted by Staphylococcus aureus (S. aureus), is a critical exotoxin in multiple infections. In this study, we found that aloe-emodin (AE), a natural compound lacking anti-S. aureus activity, could inhibit the hemolytic activity of α-toxin. Oligomerization ass...

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Detalles Bibliográficos
Autores principales:	Jiang, Lanxiang, Yi, Tian, Shen, Ziying, Teng, Zihao, Wang, Jianfeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Cellular and Infection Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6530610/ https://www.ncbi.nlm.nih.gov/pubmed/31157174 http://dx.doi.org/10.3389/fcimb.2019.00157

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