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Cyclic AMP signalling controls key components of malaria parasite host cell invasion machinery

Cyclic AMP (cAMP) is an important signalling molecule across evolution, but its role in malaria parasites is poorly understood. We have investigated the role of cAMP in asexual blood stage development of Plasmodium falciparum through conditional disruption of adenylyl cyclase beta (ACβ) and its down...

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Detalles Bibliográficos
Autores principales: Patel, Avnish, Perrin, Abigail J., Flynn, Helen R., Bisson, Claudine, Withers-Martinez, Chrislaine, Treeck, Moritz, Flueck, Christian, Nicastro, Giuseppe, Martin, Stephen R., Ramos, Andres, Gilberger, Tim W., Snijders, Ambrosius P., Blackman, Michael J., Baker, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6530879/
https://www.ncbi.nlm.nih.gov/pubmed/31075098
http://dx.doi.org/10.1371/journal.pbio.3000264