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Initial Impairment and Recovery of Vision-Related Functioning in Participants With Acute Optic Neuritis From the RENEW Trial of Opicinumab

BACKGROUND: Leucine-rich repeat and immunoglobulin domain-containing Nogo receptor-interacting protein 1 (LINGO-1) is a key suppressor of oligodendrocyte differentiation and axonal remyelination and regeneration. This analysis evaluated the potential benefit of opicinumab, a human monoclonal antibod...

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Detalles Bibliográficos
Autores principales: Petrillo, Jennifer, Balcer, Laura, Galetta, Steven, Chai, Yi, Xu, Lei, Cadavid, Diego
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Journal of Neuro-Ophthalmology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6530972/
https://www.ncbi.nlm.nih.gov/pubmed/30095536
http://dx.doi.org/10.1097/WNO.0000000000000697