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Food antigens drive spontaneous IgE elevation in the absence of commensal microbiota

Immunoglobulin E (IgE), a key mediator in allergic diseases, is spontaneously elevated in mice with disrupted commensal microbiota such as germ-free (GF) and antibiotics-treated mice. However, the underlying mechanisms for aberrant IgE elevation are still unclear. Here, we demonstrate that food anti...

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Detalles Bibliográficos
Autores principales:	Hong, Sung-Wook, O, Eunju, Lee, Jun Young, Lee, Minji, Han, Daehee, Ko, Hyun-Ja, Sprent, Jonathan, Surh, Charles D., Kim, Kwang Soon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for the Advancement of Science 2019
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6531000/ https://www.ncbi.nlm.nih.gov/pubmed/31131325 http://dx.doi.org/10.1126/sciadv.aaw1507

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