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Current trends in the features of male thyroid cancer: Retrospective evaluation of their prognostic value

This study aimed to compare the clinicopathologic characteristics and oncologic outcomes of papillary thyroid cancer (PTC) patients according to sex. Then, we validated prognostic variables to determine whether sex is a significant prognostic factor for PTC. Between January 2007 and December 2010, 1...

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Detalles Bibliográficos
Autores principales: Kim, Min Jhi, Lee, Seul Gi, Kim, Kwangsoon, Lee, Cho Rok, Kang, Sang-Wook, Lee, Jandee, Nam, Kee-Hyun, Chung, Woong Youn, Jeong, Jong Ju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6531171/
https://www.ncbi.nlm.nih.gov/pubmed/31083219
http://dx.doi.org/10.1097/MD.0000000000015559
Descripción
Sumario:This study aimed to compare the clinicopathologic characteristics and oncologic outcomes of papillary thyroid cancer (PTC) patients according to sex. Then, we validated prognostic variables to determine whether sex is a significant prognostic factor for PTC. Between January 2007 and December 2010, 1232 men and 7276 women PTC patients underwent surgery. The patient characteristics and 5-year oncologic outcomes were compared. The stepwise Cox proportional hazards model determined the significance of survival variables. Men PTC patients had more lymph node (LN) metastases than women, both in the total (P < .0001) and hemithyroidectomy (P < .0001) patients. Men and women showed similar 5-year recurrence-free survivals, both in total (P = .815) and hemithyroidectomy (P = .148) patients. The tumor size and the number of positive central nodes were associated with tumor recurrence, but not sex. Sex was not an independent prognostic factor for tumor recurrence. Multicenter clinical studies with long-term follow-ups are needed to validate these results.