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Platelet–lymphocyte ratio is not a prognostic predictor for acute paraquat-intoxicated patients: A retrospective analysis
This study aimed to investigate the prognostic predictive value of the platelet–lymphocyte ratio (PLR) in patients with acute paraquat (PQ) intoxication. A total of 107 patients with acute PQ intoxication via oral ingestion were admitted in Cangzhou Central Hospital from May 2012 to September 2018....
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer Health
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6531261/ https://www.ncbi.nlm.nih.gov/pubmed/31096516 http://dx.doi.org/10.1097/MD.0000000000015702 |
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author | Wang, Wen Jie Cao, Zong Xun Feng, Shun Yi Song, Ya Qi Zhang, Su Li Bai, Wen Jing Li, Yong |
author_facet | Wang, Wen Jie Cao, Zong Xun Feng, Shun Yi Song, Ya Qi Zhang, Su Li Bai, Wen Jing Li, Yong |
author_sort | Wang, Wen Jie |
collection | PubMed |
description | This study aimed to investigate the prognostic predictive value of the platelet–lymphocyte ratio (PLR) in patients with acute paraquat (PQ) intoxication. A total of 107 patients with acute PQ intoxication via oral ingestion were admitted in Cangzhou Central Hospital from May 2012 to September 2018. Valuable detection indices were screened out by using Cox proportional hazard regression and receiver operating characteristic (ROC) curve analyses, and their diagnostic efficiency was evaluated by using Kaplan–Meier curve. The 90-day mortality was 58.9% (63/107). The Kaplan–Meier curve showed that PLR was not associated with 90-day survival (log-rank test; P = .661). In Cox proportional hazard regression analyses, PLR was not an independent risk factor. Meanwhile, the ROC curves showed that PLR had an AUC value of 0.569 (95% confidence interval: 0.459–0.679, P = .227) in predicting 90-day survival. PLR is not a prognostic predictor for patients with acute PQ intoxication. |
format | Online Article Text |
id | pubmed-6531261 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Wolters Kluwer Health |
record_format | MEDLINE/PubMed |
spelling | pubmed-65312612019-06-25 Platelet–lymphocyte ratio is not a prognostic predictor for acute paraquat-intoxicated patients: A retrospective analysis Wang, Wen Jie Cao, Zong Xun Feng, Shun Yi Song, Ya Qi Zhang, Su Li Bai, Wen Jing Li, Yong Medicine (Baltimore) Research Article This study aimed to investigate the prognostic predictive value of the platelet–lymphocyte ratio (PLR) in patients with acute paraquat (PQ) intoxication. A total of 107 patients with acute PQ intoxication via oral ingestion were admitted in Cangzhou Central Hospital from May 2012 to September 2018. Valuable detection indices were screened out by using Cox proportional hazard regression and receiver operating characteristic (ROC) curve analyses, and their diagnostic efficiency was evaluated by using Kaplan–Meier curve. The 90-day mortality was 58.9% (63/107). The Kaplan–Meier curve showed that PLR was not associated with 90-day survival (log-rank test; P = .661). In Cox proportional hazard regression analyses, PLR was not an independent risk factor. Meanwhile, the ROC curves showed that PLR had an AUC value of 0.569 (95% confidence interval: 0.459–0.679, P = .227) in predicting 90-day survival. PLR is not a prognostic predictor for patients with acute PQ intoxication. Wolters Kluwer Health 2019-05-17 /pmc/articles/PMC6531261/ /pubmed/31096516 http://dx.doi.org/10.1097/MD.0000000000015702 Text en Copyright © 2019 the Author(s). Published by Wolters Kluwer Health, Inc. http://creativecommons.org/licenses/by-nc-nd/4.0 This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc-nd/4.0 |
spellingShingle | Research Article Wang, Wen Jie Cao, Zong Xun Feng, Shun Yi Song, Ya Qi Zhang, Su Li Bai, Wen Jing Li, Yong Platelet–lymphocyte ratio is not a prognostic predictor for acute paraquat-intoxicated patients: A retrospective analysis |
title | Platelet–lymphocyte ratio is not a prognostic predictor for acute paraquat-intoxicated patients: A retrospective analysis |
title_full | Platelet–lymphocyte ratio is not a prognostic predictor for acute paraquat-intoxicated patients: A retrospective analysis |
title_fullStr | Platelet–lymphocyte ratio is not a prognostic predictor for acute paraquat-intoxicated patients: A retrospective analysis |
title_full_unstemmed | Platelet–lymphocyte ratio is not a prognostic predictor for acute paraquat-intoxicated patients: A retrospective analysis |
title_short | Platelet–lymphocyte ratio is not a prognostic predictor for acute paraquat-intoxicated patients: A retrospective analysis |
title_sort | platelet–lymphocyte ratio is not a prognostic predictor for acute paraquat-intoxicated patients: a retrospective analysis |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6531261/ https://www.ncbi.nlm.nih.gov/pubmed/31096516 http://dx.doi.org/10.1097/MD.0000000000015702 |
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