Donation of mitochondria by iPSC-derived mesenchymal stem cells protects retinal ganglion cells against mitochondrial complex I defect-induced degeneration

Rationale: Retinal ganglion cell (RGC) degeneration is extremely hard to repair or regenerate and is often coupled with mitochondrial dysfunction. Mesenchymal stem cells (MSCs)-based treatment has been demonstrated beneficial for RGC against degeneration. However, underlying mechanisms of MSC-provid...

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Detalles Bibliográficos
Autores principales: Jiang, Dan, Xiong, Guoyin, Feng, Hong, Zhang, Zhao, Chen, Peikai, Yan, Bin, Chen, Ling, Gandhervin, Kesavamoorthy, Ma, Chuiyan, Li, Cheng, Han, Shuo, Zhang, Yuelin, Liao, Can, Lee, Tin-Lap, Tse, Hung-Fat, Fu, Qing-Ling, Chiu, Kin, Lian, Qizhou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6531297/
https://www.ncbi.nlm.nih.gov/pubmed/31149051
http://dx.doi.org/10.7150/thno.29422

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