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Bhlhe40 mediates tissue-specific control of macrophage proliferation in homeostasis and type 2 immunity
Most tissue-resident macrophage populations develop during embryogenesis, self-renew in the steady-state and expand during type 2 immunity. Whether shared mechanisms regulate the proliferation of macrophages in homeostasis and disease is unclear. Here we found that the transcription factor Bhlhe40 w...
Autores principales: | Jarjour, Nicholas N., Schwarzkopf, Elizabeth A., Bradstreet, Tara R., Shchukina, Irina, Lin, Chih-Chung, Huang, Stanley Ching-Cheng, Lai, Chin-Wen, Cook, Melissa E., Taneja, Reshma, Stappenbeck, Thaddeus S., Randolph, Gwendalyn J., Artyomov, Maxim N., Urban, Joseph F., Edelson, Brian T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6531324/ https://www.ncbi.nlm.nih.gov/pubmed/31061528 http://dx.doi.org/10.1038/s41590-019-0382-5 |
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